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Filippos D. Klironomos, Johannes Berg and Sinéad Collins How epigenetic mutations can affect genetic evolution: Model and mechanism BioEssays 35

Article first published online: 12 APR 2013 | DOI: 10.1002/bies.201200169

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Heritable epigenetic mutations have higher mutation and reversion rates than genetic mutations, but can still be acted on by natural selection. We use a model to show why pure epigenetic variation can speed up adaptation and lead to phenotype-first evolution, even on time scales where genetic evolution also happens.

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