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John B. Mumm and Martin Oft Pegylated IL-10 induces cancer immunity BioEssays 35

Version of Record online: 13 MAY 2013 | DOI: 10.1002/bies.201300004

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Pegylated IL-10 induces several essential components for cancer immunity: expansion of tumor resident CD8+ T cells, expression of IFN-γ and cytotoxic enzymes in tumor resident CD8+ T cells and antigen presentation within the tumor. PEG-IL-10 treatment leads to tumor rejection and long lasting tumor immunity.

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