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Kasturi Mitra Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation BioEssays 35

Article first published online: 14 AUG 2013 | DOI: 10.1002/bies.201300011

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The decision to remain in a proliferative state or to exit toward differentiation, quiescence, or senescence is key for cells in the developmental journey. I propose that mitochondrial morphology, controlled by mitochondrial fission-fusion proteins, is a crucial factor for guiding such cellular decisions, aberrations in which may lead to developmental anomalies.

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