Ann M. Morgan, Jennifer Lo and David E. Fisher How does pheomelanin synthesis contribute to melanomagenesis? BioEssays 35
Pheomelanin synthesis is associated with melanoma formation, but the mechanism has not been fully elucidated. We hypothesize that pheomelanin promotes formation of genotoxic reactive oxygen species, and/or that pheomelanin synthesis consumes cellular glutathione stores.
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