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Diane M. Wuest and Prof. Kelvin H. Lee Optimization of endothelial cell growth in a murine in vitro blood–brain barrier model Biotechnology Journal 7

Article first published online: 28 DEC 2011 | DOI: 10.1002/biot.201100189

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In vitro cell culture models of the blood-brain barrier (BBB) are important tools used to study cellular physiology and brain disease therapeutics. While many models exist, it is not clear whether any of these have been effectively optimized. The current work presents a sequential-screening study to optimize the culture conditions of an in vitro model of the blood-brain barrier.

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