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Mark P. Taylor, Inonge Mulako, Marla Tuffin and Prof. Don Cowan Understanding physiological responses to pre-treatment inhibitors in ethanologenic fermentations Biotechnology Journal 7

Version of Record online: 14 FEB 2012 | DOI: 10.1002/biot.201100335

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Understanding physiological responses to fermentation inhibitors is crucial to the delivery of a successful bioprocess. Pre-treatment methods inevitably generate a number of biologically detrimental compounds alongside the carbohydrates that are liberated from biomass. Inhibitors impact efficiency through decreasing both biomass and product yields. A thorough understanding of tolerance to pre-treatment inhibitors should be a major focus in ongoing strain engineering. This review can be used as a foundation that guides future metabolic engineering strategies.

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