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Yuji Mochiduki and Dr. Keisuke Okita Methods for iPS cell generation for basic research and clinical applications Biotechnology Journal 7

Version of Record online: 29 FEB 2012 | DOI: 10.1002/biot.201100356

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Currently, induced pluripotent stem (iPS) cells can be established by various methods. The factors affecting iPS reprogramming can be categorized into four groups: (i) the combination of reprogramming factors, (ii) the induction method of reprogramming factors, (iii) the culture conditions and the type of original somatic cells, and (iv) the origin of the cells. This review discusses recent advancements in the field.

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