Brandon G. Gerberich and Dr. Sujata K. Bhatia Tissue scaffold surface patterning for clinical applications Biotechnology Journal 8
Patterned biomaterials provide a platform for manipulation of cell-surface interactions: this schematic is an example of topographical engineering of wells for fabrication on a soft polymer substrate to direct cell growth and therefore tissue architecture for tissue regeneration applications. This review highlights practical applications of surface-patterned biomaterials for treatment of disease. Specifically, the review discusses applications of surface patterning for antimicrobial surfaces, neurite outgrowth, cardiac constructs, and stem cell differentiation.
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