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Kungang Li, Wen Zhang and Dr. Yongsheng Chen Quantum dot binding to DNA: Single-molecule imaging with atomic force microscopy Biotechnology Journal 8

Version of Record online: 24 OCT 2012 | DOI: 10.1002/biot.201200155

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The interaction between nanoparticles and DNA is of significance for their application. In this article, the authors use atomic force microscopy (AFM) to investigate nanoparticle-DNA interactions with quantum dots as a model nanoparticle on a single-molecule level. Experimental evidence shows that the interaction of DNA with nanoparticles changes the conformation of DNA, which may subsequently affect DNA functions.

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