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Sasha Cai Lesher-Perez, John P. Frampton and Prof. Shuichi Takayama Microfluidic systems: A new toolbox for pluripotent stem cells Biotechnology Journal 8

Version of Record online: 1 NOV 2012 | DOI: 10.1002/biot.201200206

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Conventional culture systems are often limited in their ability to regulate the growth and differentiation of pluripotent stem cells. In this review, the authors describe technologies that move small volumes of fluids (on microscales) and how they can be used with stem cells. These technologies can provide precise signals that control stem cells, causing them to self-renew (produce more stem cells) or differentiate (become any of the cells in the body). They can also be used to investigate the biology of stem cells and test their quality for medical applications. These powerful tools could one day be used to combat degenerative diseases.

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