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Mads O. Albaek, Krist V. Gernaey, Morten S. Hansen and Stuart M. Stocks Evaluation of the energy efficiency of enzyme fermentation by mechanistic modeling Biotechnology and Bioengineering 109

Version of Record online: 21 DEC 2011 | DOI: 10.1002/bit.24364

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A mechanistic model is used to evaluate the energy efficiency of cellulase production by Trichoderma reesei in pilot plant stirred tank reactors. The central part of the model is an oxygen mass transfer correlation, which is coupled to fungal growth by a viscosity prediction. The simulations confirm the inverse relationship between productivity and efficiency of the process.

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