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Stephanie Hammond, Jeffrey C. Swanberg, Shawn W. Polson and Kelvin H. Lee Profiling conserved microRNA expression in recombinant CHO cell lines using illumina sequencing Biotechnology and Bioengineering 109

Version of Record online: 23 JAN 2012 | DOI: 10.1002/bit.24415

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Illumina sequencing was used to profile the differential expression of conserved miRNAs in recombinant CHO cell lines relative to expression in CHO-K1 cells. The majority of differentially expressed miRNAs were found to be up-regulated in CHO-SEAP cells but down-regulated in CHO-tPA cells.

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