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Anne M. Ruffing and Howland D.T. Jones Physiological effects of free fatty acid production in genetically engineered Synechococcus elongatus PCC 7942 Biotechnology and Bioengineering 109

Article first published online: 9 APR 2012 | DOI: 10.1002/bit.24509

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Cyanobacteria are attractive hosts for biofuel production; however, the production of fuel precursors like free fatty acids will affect the metabolic carbon balance within the cell. This work explores how free fatty acid production in a model cyanobacterium affects cell growth, photosynthesis, and photosynthetic pigments. These physiological effects ultimately limit the capacity for biofuel synthesis and must be addressed to enable large-scale production.

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