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Franklin Lu, Poh Choo Toh, Iain Burnett, Feng Li, Terry Hudson, Ashraf Amanullah and Jincai Li Automated dynamic fed-batch process and media optimization for high productivity cell culture process development Biotechnology and Bioengineering 110

Version of Record online: 1 SEP 2012 | DOI: 10.1002/bit.24602

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Nutrient feeding of mammalian cell culture can be automated through advancement of in-line sampling and on-line probes to dynamically alter feed rates during the culture. These dynamic feeds can improve productivity and accelerate the pace of early stage process developments.

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