Peng-Yuan Wang, Tsung-Han Wu, Pen-Hsiu Grace Chao, Wei-Hsuan Kuo, Meng-Jiy Wang, Cheng-Che Hsu and Wei-Bor Tsai Modulation of cell attachment and collagen production of anterior cruciate ligament cells via submicron grooves/ridges structures with different cell affinity Biotechnology and Bioengineering 110
Anterior cruciate ligament (ACL) cells were harvested from porcine knee and cultured on the grooved surfaces with various feature sizes and surface chemistries. Cell alignment is feature size-dependent, while type I collagen production is both feature size- and surface chemistry-dependent on the grooved surfaces. This study demonstrates that grooved topography accompanied by favorable surface chemistry facilitates ACL tissue engineering.
Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf