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Kwok Ho Lam, Hsiu-Sheng Hsu, Ying Li, Changyang Lee, Anderson Lin, Qifa Zhou, Eun Sok Kim and Kirk Koping Shung Ultrahigh frequency lensless ultrasonic transducers for acoustic tweezers application Biotechnology and Bioengineering 110

Article first published online: 16 OCT 2012 | DOI: 10.1002/bit.24735

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Two types of 200-MHz lensless transducer design, LiNbO3 single crystal press-focused and ZnO self-focused transducers, were developed as an ultrasound microbeam device for an acoustic tweezers application. Tightly focused acoustic beams produced by these transducers were shown to be capable of manipulating single microspheres as small as 5 µm two-dimensionally within a range of hundreds of micrometers in distilled water. The results suggest that acoustic tweezers may be a useful tool to manipulate a single cell or molecule for biomedical applications.

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