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Hark Chuan Tan, Chye Khoon Poh, Yanli Cai, Min Thun Soe and Wilson Wang Covalently grafted BMP-7 peptide to reduce macrophage/monocyte activity: An in vitro study on cobalt chromium alloy Biotechnology and Bioengineering 110

Article first published online: 2 NOV 2012 | DOI: 10.1002/bit.24756

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Pristine cobalt chromium (CoCr) surfaces are doped with polydopamine. BMP-7 peptides are then covalently bound to the polydopamine coated CoCr. This modified CoCr surface with BMP-7 peptides helps reduce monocyte/macrophage-induced inflammation.

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