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Mathias Contie, Olivier Leger, Nicolas Fouque, Yves Poitevin, Marie Kosco-Vilbois, Nicolas Mermod and Greg Elson IL-17F co- ;expression improves cell growth characteristics and enhances recombinant protein production during CHO cell line engineering Biotechnology and Bioengineering 110

Article first published online: 23 NOV 2012 | DOI: 10.1002/bit.24763

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This study demonstrates that IL-17F expression in CHO cells confers benefit during cell line engineering for recombinant protein production. Aside from enhanced cell line productivity, improvements in cell growth during selection and subcloning allowed for an overall time saving of up to one month during clonal cell line selection.

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