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Bo Zhang, Xinpeng Ma, William Murdoch, Maciej Radosz and Youqing Shen Bioreducible poly(amido amine)s with different branching degrees as gene delivery vectors Biotechnology and Bioengineering 110

Article first published online: 23 NOV 2012 | DOI: 10.1002/bit.24772

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The branching degree of reducible PAA strongly affects its DNA binding ability, polyplexe cellular uptake and thereby gene delivery efficiency. Low branched PAA is the best in terms of these abilities.

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