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Wesley Loftie-Eaton, Mark Taylor, Kerry Horne, Marla I. Tuffin, Stephanie G. Burton and Don A. Cowan Balancing redox cofactor generation and ATP synthesis: Key microaerobic responses in thermophilic fermentations Biotechnology and Bioengineering 110

Version of Record online: 25 DEC 2012 | DOI: 10.1002/bit.24774

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Geobacillus thermoglucosidasius is an economically important organism for biofuel production yet little is known regarding its physiology. The authors measured specific transcriptional changes in the central metabolic pathways and global shifts in the proteome of this Gram-positive thermophile in response to a switch from aerobic respiration to microaerobic fermentation. Interesting results included the presence of a putative oxygen scavenging electron transport chain and a glyoxalase pathway in addition to a general response to low pO2.

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