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Jose M. Perez, Hanno Richter, Sarah E. Loftus and Largus T. Angenent Biocatalytic reduction of short-chain carboxylic acids into their corresponding alcohols with syngas fermentation Biotechnology and Bioengineering 110

Version of Record online: 15 JAN 2013 | DOI: 10.1002/bit.24786

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The potential of carboxydotrophic bacteria for conversion of short chain carboxylic acids into alcohols, using syngas as a source of electrons and energy, is demonstrated. Acetic acid, propionic acid, n-butyric acid, isobutyric acid, n-valeric acid, and n-caproic acid were converted into their corresponding alcohols. An ATP yield of 0.4–0.5 mol of ATP per mol CO consumed was calculated in the presence of hydrogen. The ratio of protons pumped versus electrons transferred via the Rnf complex is suggested to be 1.0.

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