E-mail a Wiley Online Library Link

Tony Chen, Matthew J. Hilton, Edward B. Brown, Michael J. Zuscik and Hani A. Awad Engineering superficial zone features in tissue engineered cartilage Biotechnology and Bioengineering 110

Version of Record online: 27 DEC 2012 | DOI: 10.1002/bit.24799

Thumbnail image of graphical abstract

A major challenge in cartilage tissue engineering is reproducing the native extracellular matrix anisotropy. This study uses a hydrodynamic rotating bioreactor to mimic aspects of the flow fields produced during joint sliding and characterizes the effect of these hydrodynamic fields on the anisotropy of tissue engineered cartilage hydrogels and the production of surface zone specific matrix proteins and structural alignment.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field