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Rainer Fischer, Mariola Fotin-Mleczek, Hansjörg Hufnagel and Roland Brock Break on through to the Other Side—Biophysics and Cell Biology Shed Light on Cell-Penetrating Peptides ChemBioChem 6

Version of Record online: 27 OCT 2005 | DOI: 10.1002/cbic.200500044

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Finding the way in. Despite the broad acceptance of cell-penetrating peptides (CPPs) as molecular carriers, the details of the mode of cellular internalization and membrane permeation of these molecules still remain elusive. A detailed mechanistic understanding of the import mechanism will depend on a close interaction between cell biology and biophysics.

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