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Rakesh N. Veedu, Birte Vester and Jesper Wengel Enzymatic Incorporation of LNA Nucleotides into DNA Strands ChemBioChem 8

Article first published online: 22 FEB 2007 | DOI: 10.1002/cbic.200600501

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Unlocking uses of locked nucleic acids: LNA nucleoside 5′-triphosphates have been synthesized, and their ability to serve as substrates for polymerases have been investigated. Phusion high-fidelity DNA polymerase was found to be an efficient enzyme for incorporating LNA nucleoside 5′-triphosphates into DNA strands.

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