E-mail a Wiley Online Library Link

Anne-Sophie Rebstock, Cristina Visintin, Elisabetta Leo, Cristina Garcia Posada, Sarah R. Kingsbury, Gareth H. Williams, Kai Stoeber and David L. Selwood Modular Assembly Using Sequential Palladium Coupling Gives Easy Access to the SMoC Class of Cellular Transporters ChemBioChem 9

Article first published online: 4 JUL 2008 | DOI: 10.1002/cbic.200800153

Thumbnail image of graphical abstract

Have a lift: The transducing ability of the third helix of transcription factor homeodomains is effectively mimicked by a biphenyl system displaying guanidine groups (see scheme). The biphenyl class of small-molecule carriers (SMoCs) can carry biomolecules into a wide variety of cell types. A “combinatorial” approach to the synthesis of SMoCs is described using sequential Pd0 coupling chemistry to assemble the molecules from highly functionalized building blocks.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field