E-mail

E-mail a Wiley Online Library Link

Rajesh Mishra, Daniel Sellin, Diana Radovan, Andrea Gohlke and Roland Winter Inhibiting Islet Amyloid Polypeptide Fibril Formation by the Red Wine Compound Resveratrol ChemBioChem 10

Version of Record online: 22 JAN 2009 | DOI: 10.1002/cbic.200800762

Thumbnail image of graphical abstract

Grapes for amyloids: The red wine compound resveratrol can effectively inhibit the formation of IAPP amyloid that is found in type II diabetes. Our in vitro inhibition results do not depend on the antioxidant activity of resveratrol. Further, the markedly enhanced cell survival in the presence of resveratrol also indicates that the small oligomeric structures that are observed during β-sheet formation are not toxic and could be off-pathway assembly products.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH