E-mail a Wiley Online Library Link

Dr. Karine Guitot, Dr. Maud Larregola, Dr. Tarun K. Pradhan, Dr. Jean-Luc Vasse, Prof. Solange Lavielle, Prof. Philippe Bertus, Prof. Jan Szymoniak, Prof. Olivier Lequin and Prof. Philippe Karoyan The Combination of Prolinoamino Acids and Cyclopropylamino Acids Leads to Fully Functionalized, Stable β-Turns in Water ChemBioChem 12

Version of Record online: 29 MAR 2011 | DOI: 10.1002/cbic.201000707

Thumbnail image of graphical abstract

Tight turns: Peptide mimics based on combinations of cis-3-prolinoamino acids (prolinohomotryptophan) and (Z)-2,3-methanoamino acids (c3Arg or c3Lys) form stable β-turns in water. This combination of constraints allows one to mimic turns with side chain conformations not accessible with the previously reported strategy involving combinations of prolinoamino acids and N-methylamino acids.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field