Prof. Dr. Rob M. J. Liskamp, Dr. Dirk T. S. Rijkers, Dr. John A. W. Kruijtzer and Dr. Johan Kemmink Peptides and Proteins as a Continuing Exciting Source of Inspiration for Peptidomimetics ChemBioChem 12
Building bridges: The design and development of peptidomimetics is an expanding research area and yields molecules that can improve on the function of their “natural” parent peptides—with tempting potential for novel therapeutics. We review here several different directions in exciting areas of oligomeric peptidomimetics, hybrids and covalent control of shape and secondary structure folding by alternatives to disulfide bridges.
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