Prof. Young-Ho Lee, Prof. Takahisa Ikegami, Dr. Daron M. Standley, Prof. Kazumasa Sakurai, Prof. Toshiharu Hase and Prof. Yuji Goto Binding Energetics of Ferredoxin-NADP+ Reductase with Ferredoxin and Its Relation to Function ChemBioChem 12
Protein in motion: Ferredoxin (Fd) bound ferredoxin-NADP+ reductase (FNR) elevates and lowers its flexibility, simultaneously, over wide timescales (see figure). Increases in conformational fluctuations of FNR stabilize the Fd–FNR complex. The C-terminal dynamics of FNR controls negative cooperativity between Fd and NADP(+).
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