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Elena Pazos, Jesús Mosquera, Prof. Dr. M. Eugenio Vázquez and Prof. Dr. José L. Mascareñas DNA Recognition by Synthetic Constructs ChemBioChem 12

Article first published online: 29 JUL 2011 | DOI: 10.1002/cbic.201100247

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Synthetic DNA stickers: Inspired by the natural transcription factors that regulate gene expression, researchers have long pursued the development of synthetic sequence-specific DNA-binding agents. In this review we discuss several types of DNA-binding platforms as well as some of the tactics that have been used to control their activity.

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