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Dr. Tobias J. Zimmermann, Marco Bürger, Prof. Dr. Etsu Tashiro, Dr. Yasumitsu Kondoh, Nancy E. Martinez, Dr. Kristina Görmer, Sigrid Rosin-Steiner, Dr. Takeshi Shimizu, Dr. Shoichiro Ozaki, Dr. Katsuhiko Mikoshiba, Dr. Nobumoto Watanabe, Prof. Dr. Dennis Hall, Dr. Ingrid R. Vetter, Prof. Dr. Hiroyuki Osada, Dr. Christian Hedberg and Prof. Dr. Herbert Waldmann Boron-Based Inhibitors of Acyl Protein Thioesterases 1 and 2 ChemBioChem 14

Version of Record online: 13 DEC 2012 | DOI: 10.1002/cbic.201200571

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Ras depalmitoylation inhibitors: Different boronic and boronic acid inhibitors were found to target acyl protein thioesterases on a microarray screening chip. Individual inhibitors also display appreciable isoenzymatic specificity for APT2; this makes these boronic acids a class of APT inhibitors with specificity for one of the APTs.

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