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Flavia A. Mercurio, Dr. Daniela Marasco, Dr. Luciano Pirone, Dr. Pasqualina L. Scognamiglio, Dr. Emilia M. Pedone, Prof. Maurizio Pellecchia and Dr. Marilisa Leone Heterotypic Sam–Sam Association between Odin-Sam1 and Arap3-Sam: Binding Affinity and Structural Insights ChemBioChem 14

Version of Record online: 13 DEC 2012 | DOI: 10.1002/cbic.201200592

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Heterotypic Sam–Sam complex: We have characterized the interaction between Odin-Sam1 and Arap3-Sam by NMR, SPR, ITC, and molecular docking techniques. The two proteins bind in the low micromolar range, and might adopt the mid-loop/end-helix model typical of several Sam–Sam complexes.

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