E-mail a Wiley Online Library Link

Daniela Boettger and Christian Hertweck Molecular Diversity Sculpted by Fungal PKS–NRPS Hybrids ChemBioChem 14

Version of Record online: 7 DEC 2012 | DOI: 10.1002/cbic.201200624

Thumbnail image of graphical abstract

It's all in the mix: The combination of polyketides and amino acids gives rise to a diverse group of secondary metabolites. In fungi, the underlying biosynthetic enzymes code for type I iterative PKS–NRPS hybrids. This review provides an overview of all characterized fungal PKS–NRPS hybrids and their biosynthetic machinery, and highlights molecular engineering approaches.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field