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Ayuko Meguro, Dr. Takeo Tomita, Prof. Makoto Nishiyama and Prof. Tomohisa Kuzuyama Identification and Characterization of Bacterial Diterpene Cyclases that Synthesize the Cembrane Skeleton ChemBioChem 14

Version of Record online: 6 FEB 2013 | DOI: 10.1002/cbic.201200651

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Digging up skeletons: We report the identification and the functional characterization of two terpene cyclases (DtcycA and DtcycB) that were mined from the genome of Streptomyces sp. SANK 60404. DtcycA and DtcycB are novel bacterial diterpene cyclases for the synthesis of the cembrane skeleton.

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