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Dr. Michael Rettig, Prof. Markus W. Germann, Shuo Wang and Prof. W. David Wilson Molecular Basis for Sequence-Dependent Induced DNA Bending ChemBioChem 14

Version of Record online: 25 JAN 2013 | DOI: 10.1002/cbic.201200706

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Ligand-induced DNA bending: In contrast to the situation for A-tract DNA, binding of netropsin results in the bending of alternating AT DNA towards the minor groove. This was shown by NMR, PAGE mobility, and rMD studies.

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