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Stefanie Julia Kellermann, Anna Katharina Rath and Dr. Andrea Rentmeister Tetramolecular Fluorescence Complementation for Detection of Specific RNAs in Vitro ChemBioChem 14

Article first published online: 9 JAN 2013 | DOI: 10.1002/cbic.201200734

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Short fuses: RNA can be detected sequence specifically by using two RNA binding proteins fused to short strands derived from GFP and an additional large GFP fragment. The tetramolecular system has a high signal-to-noise ratio, discriminates between closely related RNA, and works in RNA preparations as well as E. coli cell lysate.

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