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Dr. Lai Yue Chan, Veronica M. Zhang, Dr. Yen-hua Huang, Dr. Norman C. Waters, Dr. Paramjit S. Bansal, Prof. David J. Craik and Prof. Norelle L. Daly Cyclization of the Antimicrobial Peptide Gomesin with Native Chemical Ligation: Influences on Stability and Bioactivity ChemBioChem 14

Version of Record online: 20 FEB 2013 | DOI: 10.1002/cbic.201300034

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Going round in cycles: The use of native chemical ligation to link the N and C termini of gomesin with a one-residue linker is reported. These findings support the generalization of the concept of using backbone cyclization to enhance the therapeutic potential of peptides.

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