E-mail a Wiley Online Library Link

Stephanie Voss and Dr. Yao-Wen Wu Tandem Orthogonal Chemically Induced Dimerization ChemBioChem 14

Version of Record online: 12 AUG 2013 | DOI: 10.1002/cbic.201300446

Thumbnail image of graphical abstract

Switch on and off: Chemically induced dimerization (CID) has been shown to be a powerful tool for dissecting and emulating signaling pathways. What has been missing so far is the reproduction of reversibility in signal transduction. This problem could be resolved by applying two orthogonal CID systems in tandem, which allow switching signaling on and off through a double translocation strategy.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field