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Osamu Imataki, Naoki Watanabe, Kensuke Matsumoto and Makiko Uemura Chronic myelomonocytic leukemia presenting with polyserositis due to an immune-mediated monocyte activation Clinical Case Reports 2

Version of Record online: 28 FEB 2014 | DOI: 10.1002/ccr3.55

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Monocytosis is often profoundly implicated in chronic myelomonocytic leukemia (CMML). We diagnosed a 63-year-old woman with CMML involving hetero-chronological systemic polyserositis with infiltrating benign monocytes. The patient's pleural effusion was eliminated completely with corticosteroid therapy. We speculate that our case represents an immunologic reaction with activated monocytes triggered by infection.

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