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Dr. Damien Mailhol, Dr. Juan-Carlos Castillo, Dr. Kishor Mohanan, Dr. Rodrigo Abonia, Dr. Yoann Coquerel and Prof. Dr. Jean Rodriguez Practical and Efficient Organocatalytic Enantioselective α-Hydroxyamination Reactions of β-Ketoamides ChemCatChem 5

Version of Record online: 18 FEB 2013 | DOI: 10.1002/cctc.201200723

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Constrained chiral center: The first general, efficient and highly enantioselective α-hydroxyamination reactions of carbonyl compounds are described, securing a practical synthetic access to conformationally constrained α-amino acid derivatives exhibiting a quaternary chiral center at the α-position.

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