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Wenhan Zhang and Prof. Joseph M. Ready Optically Active Allenes from an Allylic Substitution/Isomerization Sequence ChemCatChem 5

Article first published online: 11 SEP 2013 | DOI: 10.1002/cctc.201300663

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It takes two to trisubstitute: A two-step procedure involving enantioselective allylic alkylation followed by 1,3 hydrogen shift enables the catalytic asymmetric synthesis of trisubstituted allenes.

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