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Robert Westphal, Sascha Jansen, Constantin Vogel, Prof. Jürgen Pleiss, Prof. Michael Müller, Dr. Dörte Rother and Prof. Martina Pohl MenD from Bacillus subtilis: A Potent Catalyst for the Enantiocomplementary Asymmetric Synthesis of Functionalized α-Hydroxy Ketones ChemCatChem 6

Version of Record online: 4 NOV 2013 | DOI: 10.1002/cctc.201300690

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Welcome to the familee: We characterize a new member of the thiamine enzyme family for the enantiocomplementary 1,2-carboligation, and engineered variants with remarkable (S)-selectivity for the synthesis of meta-substituted 5-hydroxy-4-oxo-arylpentanoates.

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