E-mail a Wiley Online Library Link

Dr. Rachel S. Heath, Dr. Marta Pontini, Dr. Beatrice Bechi and Prof. Nicholas J. Turner Development of an R-Selective Amine Oxidase with Broad Substrate Specificity and High Enantioselectivity ChemCatChem 6

Version of Record online: 22 JAN 2014 | DOI: 10.1002/cctc.201301008

Thumbnail image of graphical abstract

Nicotine rush: An R-selective amine oxidase based on 6-hydroxy-D-nicotine oxidase (6-HDNO) with broadened substrate scope and high enantioselectivity has been developed. The engineered 6-HDNO enzyme is applied to the preparative deracemization of a range of racemic amines to yield S-configured products, for example, (S)-nicotine, in high ee.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field