Dr. Antoine Simonneau, Dr. Youssef Harrak, Louis Jeanne-Julien, Dr. Gilles Lemière, Dr. Virginie Mouriès-Mansuy, Dr. Jean-Philippe Goddard, Prof. Dr. Max Malacria and Prof. Dr. Louis Fensterbank Inside Cover: Ring Expansions Within the Gold-Catalyzed Cycloisomerization of O-Tethered 1,6-Enynes. Application to the Synthesis of Natural-Product-like Macrocycles (ChemCatChem 5/2013) ChemCatChem 5
Nature's first green is gold The cover picture shows the gold(I)-catalyzed cycloisomerization of O-tethered 1,6-enynes, which proceeds via fused tricyclic compounds with a dihydropyran moiety. As described in their Communication on p. 1096 ff., L. Fensterbank et al. continue this ring-expansion with a two-step sequence for the transformation of the cyclized compounds into valuable ketomacrolactones, with a motif that echoes natural products. And all this in the golden surroundings of Paris!
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