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Yujun Song, Xiaohui Wang, Chao Zhao, Konggang Qu, Jinsong Ren and Xiaogang Qu Label-Free Colorimetric Detection of Single Nucleotide Polymorphism by Using Single-Walled Carbon Nanotube Intrinsic Peroxidase-Like Activity Chemistry - A European Journal 16

Version of Record online: 28 FEB 2010 | DOI: 10.1002/chem.200902643

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SWNTs possess intrinsic peroxidase-like activity, catalyzing the reaction of peroxidase substrate 3,3,5,5-tetramethylbenzidene (TMB) in the presence of H2O2 to produce a color reaction. Here SWNTs have been used for label-free colorimetric detection of disease-associated single-nucleotide polymorphism with a direct detection limit of 1 nM.

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