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Dr. Francesco Turci, Dr. Maura Tomatis, Dr. Isidoro G. Lesci, Prof. Norberto Roveri and Prof. Bice Fubini The Iron-Related Molecular Toxicity Mechanism of Synthetic Asbestos Nanofibres: A Model Study for High-Aspect-Ratio Nanoparticles Chemistry - A European Journal 17

Version of Record online: 24 NOV 2010 | DOI: 10.1002/chem.201001893

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The role of iron unveiled: An inert synthetic iron-free asbestos nanofibre has been used to clarify at the atomic level the role of iron in fibre-induced toxicity. Upon progressive iron loading, production of reactive oxygen species was inversely related to iron clustering, with low-iron fibres being more reactive than highly loaded ones (see picture).

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