E-mail a Wiley Online Library Link

Dr. Olga García Mancheño, Pia Tangen, Renate Rohlmann, Roland Fröhlich and Dr. José Alemán Synthesis of Chiral Cyclic Nitrones by Asymmetric Addition of β-Ketosulfones to Nitroalkenes followed by Reductive Cyclization Chemistry - A European Journal 17

Version of Record online: 24 NOV 2010 | DOI: 10.1002/chem.201001914

Thumbnail image of graphical abstract

An addition to the family: Thiourea cinchona alkaloids catalyze the addition of β-ketosulfones to nitroalkenes. The readily obtained addition products can be selectively transformed into chiral nitrones by reduction of the nitro group and cyclization in situ (up to 99:1 e.r. and >98:2 d.r.; see scheme).

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field