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Dr. Maria Carolina de Ceglie, Dr. Biagia Musio, Dr. Francesco Affortunato, Dr. Anna Moliterni, Dr. Angela Altomare, Prof. Saverio Florio and Prof. Dr. Renzo Luisi Solvent- and Temperature-Dependent Functionalisation of Enantioenriched Aziridines Chemistry - A European Journal 17

Version of Record online: 12 NOV 2010 | DOI: 10.1002/chem.201002172

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Choose the right conditions! When starting from enantioenriched parent aziridines, it is possible to address the regio- and stereoselectivity of the lithiation/electrophile trapping sequence by finely tuning the reaction conditions. Highly enantioenriched functionalised aziridines could be obtained (see graphic) and their usefulness has been demonstrated.

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