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Prof. Timothy J. Donohoe, Cedric K. A. Callens, Dr. Aida Flores, Adam R. Lacy and Akshat H. Rathi Recent Developments in Methodology for the Direct Oxyamination of Olefins Chemistry - A European Journal 17

Version of Record online: 16 DEC 2010 | DOI: 10.1002/chem.201002323

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Spoilt for choice: The direct conversion of an alkene to a vicinal amino alcohol derivative (oxyamination, see scheme) is one of the most important approaches to this versatile functional group, which is found in scores of biologically active molecules and other interesting synthetic targets such as ligands and auxiliaries. This review provides the reader with a tour of the methods that have emerged in the last few years so one can appreciate the myriad of different metals and reagents that can accomplish the oxyamination of alkenes.

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