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Hyang Yeon Lee, Jae Jeong Lee, Jongmin Park and Prof. Seung Bum Park Inside Cover: Development of Fluorescent Glucose Bioprobes and Their Application on Real-Time and Quantitative Monitoring of Glucose Uptake in Living Cells (Chem. Eur. J. 1/2011) Chemistry - A European Journal 17

Article first published online: 5 JAN 2011 | DOI: 10.1002/chem.201090249

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The perturbation… … of glucose uptake in organisms is an essential barometer in various metabolic diseases. In their Full Paper on page 143 ff. S. B. Park et al. report on a novel fluorescent glucose bioprobe that can translocate into cytoplasm by glucose-specific transport systems through the competition with D-glucose. Unlike reported glucose bioprobes, such as NBDGs and 2-deoxyglucoses, this fluorescent glucose bioprobe allows the real-time and quantitative measurement of glucose uptake in living cells.

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